Fact sheet: Focus on G6PD Deficiency

7 June 2019
Medicines for Malaria Venture

Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme that catalyses the first step in the pentose phosphate pathway. G6PD deficiency impairs the ability of the red blood cell to form NADPH (nicotinamide adenine dinucleotide phosphate), causing the cell to be susceptible to oxidative stress.