Five day primaquine therapy--an evaluation of radical curative activity against vivax malaria infection.

01 Nov 1973
Contacos PG, Coatney GR, Collins WE, Briesch PE, Jeter MH

The radical curative efficacy of the 5-day primaquine regimen for vivax malaria was assessed in nonimmune volunteers infected with a West Pakistan strain of Plasmodium vivax. Treatment of each primary attack was with chloroquine, 1,500 mg base followed by primaquine, 15 mg base daily for 5 consecutive days. There was a 100% failure rate of radical cure for the 5-day primaquine regimen. Data on the pattern of relapse activity for this strain are included.

Full text article: http://www.ajtmh.org/content/journals/10.4269/ajtmh.1973.22.693