PVIVAX

Knowledge sharing for relapsing malaria

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  • P. vivax
    • Malaria and P. vivax malaria
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    • Diagnostic methods
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    • Diagnosing severe vivax malaria
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      • G6PD Global Prevalence
      • G6PD diagnostics
      • Types of G6PD clinical diagnostic tests
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Photo: Hadynyah/istock

About the P. vivax information hub 

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Photo: Hadynyah/istock
Photo: Schumann/MMV

Video on life-changing treatment to cure relapsing P. vivax malaria.

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Photo: Schumann/MMV
Photo: Cristina Donini/MMV

Vivax Working Group Annual meeting 

15 -17th October Nepal

 

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Photo: Cristina Donini/MMV
Photo: MMV

The Malaria in Pregnancy (MiP) Library now available on WWARN. 

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Photo: MMV

Featured resources

24 Jul 2019

Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

Primaquine prevents Plasmodium vivax malaria relapses, but adherence to the standard 14-day regimen is poor. We aimed to assess the efficacy of a shorter course (7 days) of primaquine for radical cure of vivax malaria.

Lancet
Peer-reviewed article
15 Apr 2019

2018 in review: five hot topics in tropical medicine

Tafenoquine for Plasmodium vivax malaria is heralded among the five new developments in the field of tropical medicine in 2018. 

Tropical Diseases, Travel Medicine and Vaccines
Peer-reviewed article
01 Jul 2015

Control and elimination of Plasmodium vivax malaria – A technical brief

This technical brief developed by the World Health Organisation reviews the biological characteristics, geographical distribution and worldwide burden of P. vivax malaria. 

World Health Organisation
Strategy
15 Sep 2015

Implementation of G6PD testing and radical cure in P. vivax endemic countries: considerations

This technical brief features discussions on translating guidelines into policy and strategy in programmes for the control and elimination of Plasmodium vivax malaria.

World Health Organisation
Guidance Document
1

News

Photo: PATH

Expert Review Panel for Diagnostics approval expands access to a G6PD deficiency test that supports P. vivax malaria treatment and elimination initiatives

03 Oct 2019
Photo: Marco Corsi/Sigma Tau

New maps could show how to beat malaria

24 Jun 2019

PATH and MMV launch 5-year global initiative to support elimination of relapsing malaria

23 Apr 2019

New opportunities to prevent P. vivax malaria relapse

25 Feb 2019
View news and events
1

Events

Photo: Anna Wang/MMV
15
Oct
2019

Vivax working group annual meeting

This 2-day invitation-only event is focused on the development of strategies for implementation of new tools and approaches to radical cure for malaria.

15-17th October
Nepal
Photo: Pearl Gan/MMV
20
Nov
2019

68. Annual Meeting of the American Society of Tropical Medicine and Hygiene

20 - 24 November 2019
National Harbor, Maryland, USA
1

Publications

24 Sep 2019

A molecular barcode and online tool to identify and map imported infection with Plasmodium vivax

 Traditionally, patient travel history has been used to identify imported cases, but the long-latency liver stages confound this approach in Plasmodium vivax. Molecular tools to identify and map imported cases offer a more robust approach.

Bio rxiv
Peer-reviewed article
Aug 19 2019

Splenic Infarction in Plasmodium vivax Infection in South Korea.

The research investigated the prevalence and characteristics of splenic complications in patients with vivax malaria from 2005 to 2017 in a university hospital.

Am J Trop Med Hyg.
Peer-reviewed article
03 Sep 2019

Emergence of P. vivax resistance to chloroquine in French Guiana.

The objective of this study was to collect data on chloroquine resistance in French Guiana by associating a retrospective evaluation of the therapeutic efficacy and an analysis of recurrent parasitemia from any patients.

AntiMicrob Agents Chemother
Peer-reviewed article
19 Aug 2019

Antibodies to Plasmodium vivax reticulocyte binding protein 2b are associated with protection against P. vivax malaria in populations living in low malaria transmission regions of Brazil and Thailand

Our results indicate that PvRBP2b warrants further preclinical development as a blood-stage vaccine candidate against P. vivax. Total IgG responses to PvRBPs were also shown to be promising immunological markers of exposure to P. vivax infection.

PLoS Negl Trop Dis.
Peer-reviewed article
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