Chloroquine-resistant Plasmodium vivax malaria in infancy and childhood.

Cases of malaria are increasing day by day in the vicinity of Delhi. A large number of cases attends this department for screening of malarial parasites. Several thousand cases were screened since October 1976 and only 10 cases were detected who were resistant to chloroquine treatment. The peripheral blood smears on repeated examination even after chloroquine therapy given on more than 2 to 3 occasions showed heavy parasitisation ofP. vivax. Subsequent treatment with primaquine for 5 days was inadequate as persistence of P. vivax was present. Primaquine therapy extended to 14 days showed complete disappearance ofP. vivax from the peripheral blood on subsequent repeated examinations.

Full text article: https://link.springer.com/article/10.1007%2FBF02749316