Combined chloroquine-primaquine therapy against vivax malaria.

The efficacy of the therapeutic regimen consisting of eight weekly doses of combined chloroquine-primaquine was evaluated against a South Victnam (SV) strain of vivax malaria and Chesson strain vivax. The chloroquine was given at a dose of 300 mg base and the primaquine at 45 mg base. Against the SV strain of vivax there was a protective rate of 90% and a radical curative rate of 100% for this therapeutic regimen. The efficacy against Chesson strain vivax was lower. Relapse pattern characteristics on the SV strain are presented.

Full text article: http://www.ajtmh.org/content/journals/10.4269/ajtmh.1974.23.310