Drug resistant Plasmodium vivax malaria.

The recognition of resistance to proguanil, pyrimethamine and, later chloroquine in some strains of Plasmodium falciparum, over 40 years ago, signaled the ability of these malaria parasites to survive antimalarial chemotherapy by the selection of resistant mutants. Since then, clinicians and biologists have defines resistance from different perspectives, the former focusing on the host and the latter on the parasite.

Full text article: https://academic.oup.com/jac/article/40/6/749/892947