Primaquine and quinocide as curative agents against sporozoite-induced Chesson strain vivax malaria.

Primaquine was synthesized by Elberfield (1946) and its pronounced effectiveness against Chesson strain vivax was demonstrated by Edgcomb et al (1950). In the military installations in the United States, it was highly effective for the racdical cure of Korean vivax malaria (Garrison et al, 1952; Alving et al, 1953; Coatney et al, 1953). It was first used on a large scale when the United States troops returned home from Korea by ship.

Full text article: https://apps.who.int/iris/bitstream/handle/10665/64911/WHO_Mal_327.pdf?s...