Studies in human malaria; trials of quinacrine, colchicine (SN 12,080) and quinine against Chesson strain vivax malaria.

When it became evident in 1943 and 1944 that vivax malaria acquired by troops in the Southwest Pacific differed in its relapse characteristics from infections caused by such carefully demonstrated strains as the St. Elizabeth, McCoy and Madagascar, arrangements were made for the study of the Pacific strain in the United States. At the suggestion for the Board for Coordination of Malarial Studies, vivax parasites were obtained from a soldier newly returned from New Guinea and under treatment from relapsing malaria at Hermon General Hospital (Ehrman et al., 1945).