Studies on synthetic antimalarial drugs; the effect of therapeutic courses of paludrine on the relapse-rate of vivax malaria.

01 Dec 1947
ANDREWS WH, GALL D, MAEGRAITH BG

This paper deals with the relapse-rate of vivax malaria after certain paludrine-dosage régimes. It is divided into two sections: into the first, a comparison is made between the effects of a standard mepacrine therapeutic course and of two different dosage regimes of paludrine on the relapse rate of vivax malaria; in the second, the effects are described of a therapeutic dose of paludrine followed by one-weekly dose for six months. For the sake of clarity, the cases in the first section are referred to as the first series, and those in the second section as the second series.